Botox Treatment for Migraines

Commonly known for smoothing wrinkles and improving or enhancing one’s looks and features, Botox is now gaining popularity among adults in another area – treating chronic migraine headaches. According to research about 12% of the American population today is affected with migraine, and in 2010, the FDA stated that Botox injections can prove to be effective in preventing migraines, which are characterized as debilitating headaches that result in intense pulsing or throbbing pains.

Migraines are also referred to as ‘sick headaches’, since they generally occur along with nausea and sensitivity to sound and light. In a recent news release, the MD of the FDA Russell Katz stated that patients suffering from chronic migraines experience headaches that can last for more than 14 days in a single month! This critically affects family and social life, hence other alternative and effective treatment approaches are much sought after to make it bearable

Botox  – An Alternative Treatment to End Pain

Botox is derived from the word botulinum toxin, a neurotoxin produced by botulism-causing bacteria. When purified and administered in small doses around specific areas, this neurotoxin can temporarily reduce muscular contractions for about six months. Botox penetrates the nerve ends and blocks chemicals involved in pain transmission.
According to the FDA, Botox injections for treating chronic migraine headaches should be administered by qualified medical specialists after intervals of every 12 weeks. This involves a number of injections, specifically 31 labeled doses, injected around seven distinct areas of the neck and head, with the intent of suppressing future symptoms. This treatment regime is expected to provide relief lasting for up to three months, based on the patient’s overall well-being

 How Does This Work for Migraines?

Now that you know the basics, the medical team have compiled some crucial information that you must consider before getting yourself into a Botox treatment regime.

Who Will the Migraine Treatment Work for?

The makers of Botox, Allergan Inc., have emphasized that the FDA’s approval for this sort of treatment applies only to those who suffer from ‘chronic migraine’, which is defined as a severe neurological disorder in which patients have a headache for a minimum of 15 days every month, lasting for about four hours a day and even longer. The treatment is comparatively less beneficial for episodic migraines (headaches lasting for 0 to 14 days per month) or tension-type headaches (mild or moderate headaches brought on by muscular contractions in the head and neck regions).

According to an investigative review published in the Journal of Medical Association in 2010, 31 clinical trials of treating migraine headaches with Botox were examined which included 5,313 patients. 27 of these trials compared placebos to Botox and the remaining four were randomized clinical trials comparing headache medications (amitriptyline (Elavil), topiramate (Topamax, prednisone and valproate (Depakote) to Botox.

An analysis of the placebo-controlled trials showed that Botox contributed towards an average of ‘two fewer headaches’ a month for both, chronic migraine patients and chronic daily headaches. The report also confirmed that Botox was of no help for those suffering from episodic migraines or chronic tension-type headaches.

How Effective is the Treatment for Migraines?

According to Dr. Jeffery Jackson, Professor of Medicine at the Medical College of Wisconsin, Milwaukee, Botox is a ‘preventive’ medication for chronic migraine headaches and not an ‘abortive’ one. Moreover, the effect is also ‘small to modest’ for chronic sufferers. Nevertheless, Dr. Jackson encouraged patients to give Botox a try, since it has few side-effects and even a modest improvement in symptoms can be life-changing.

What are the Side effects?

Despite affecting less than 10% of chronic migraine sufferers, Botox treatment does have some side effects. The most common side-effect experienced by 9% of the patients in clinical trials was neck pain. Rare side effects reported include headaches, minimal or partial facial paralysis, drooping eyelids, bronchitis, muscle weakness, and musculoskeletal stiffness, pain in ligaments, bones and tendons, muscle spasms, and hypertension.

Having said that, it must be remembered that every individual is different, and for some the risks may outweigh the benefits. Certain patients have reported feelings of severe choking, numbness in the head and sensitivity to touch. However, most testimonials are positive and encouraging enough for people to consider giving Botox treatment a try.

How Many Trials Are Needed for a Fair Assessment?

For a fair trial, the patient will receive injections two to three times over a period of six to nine months. This is useful since the muscles need some time to train themselves to relax, hence recurrent doses are required. Also, some patients have reported that their side-effects varied every time they got treated. Therefore, don’t give up treatment on the first try – reconsider whether you are up for it after at least three tries.

How much does Botox for Migraines Cost?

Botox for treating chronic migraine headaches is a high cost-high benefit decision. A typical dose of Botox for migraine is 155 units and Botox for treating migraine costs £750 at our Chelsea clinic.


There are many safe, effective and non-injectable ways to prevent migraine headaches, such as magnesium, Meditation, Yoga, and physiotherapy. So before you chose to try Botox, weigh the pros and cons carefully.

 The Role of Botox in Migraine Treatment: Alleviating Chronic Migraines


Chronic migraines can have a profound impact on an individual’s quality of life, causing intense pain, debilitating symptoms, and disruption of daily activities. While Botox is widely known for its cosmetic applications, it has also emerged as an effective treatment option for chronic migraines. In this article, we will delve into the role of Botox in migraine treatment, exploring its mechanism of action, scientific evidence, benefits, and considerations. Understanding the potential of Botox can empower migraine sufferers to seek appropriate care and find relief from this challenging condition.


How Botox Works in Migraine Treatment

Targeting Muscle Hyperactivity


Botox, also known as Botulinum Toxin Type A, works by temporarily paralyzing or relaxing specific muscles involved in migraine development. Migraines can be triggered by muscle hyperactivity, leading to pain and other associated symptoms. By injecting Botox into specific muscle areas, it inhibits the release of neurotransmitters responsible for transmitting pain signals, reducing muscle hyperactivity and thereby mitigating migraines.


Modulating Nerve Signalling


Botox may also modulate nerve signalling pathways involved in migraine development. It disrupts the release of pain neurotransmitters and interferes with the sensitivity of nerve endings responsible for transmitting pain signals. This modulation helps reduce the intensity and frequency of migraine episodes, providing relief for sufferers.


Scientific Evidence and Clinical Studies

FDA Approval and Guidelines


In 2010, the U.S. Food and Drug Administration (FDA) approved Botox for the preventive treatment of chronic migraines. This approval was based on clinical trials that demonstrated the efficacy and safety of Botox in reducing the frequency of migraines. According to the FDA guidelines, Botox should be administered by healthcare professionals who have received specialized training in the use of the treatment for migraines.


Efficacy and Duration of Relief


Clinical studies have shown that Botox treatment can significantly reduce the frequency, severity, and duration of migraines. The effects of Botox injections can last for several months, providing sustained relief for migraine sufferers. In some cases, patients experience long-term remission from migraines even after discontinuing Botox treatment.


Benefits of Botox for Migraines

Reduction in Migraine Frequency and Severity


One of the key benefits of Botox for migraines is a reduction in the frequency and severity of migraine episodes. Clinical studies have shown that Botox treatment can lead to a significant decrease in the number of monthly migraines experienced by patients. This reduction in migraine frequency can greatly improve a patient’s quality of life and overall well-being.


Improved Response to Medication


In addition to reducing the frequency of migraines, Botox treatment has been found to enhance the response to acute migraine medications. It can make these medications more effective in managing migraines when they do occur. This combined approach can provide more comprehensive relief for migraine sufferers.


Potential for Long-Term Remission


Long-term Botox treatment may induce a state of remission for some migraine sufferers. Remission refers to a significant reduction in the frequency and intensity of migraines even after discontinuing Botox treatment. While not all patients experience long-term remission, the potential for sustained improvement makes Botox a promising option for migraine management.


Considerations and Safety

Ideal Candidate for Botox Treatment


Not everyone with migraines is an ideal candidate for Botox treatment. Typically, Botox is recommended for individuals who experience chronic migraines, which are defined as having 15 or more headache days per month, with at least eight of those days meeting the criteria for migraines. A healthcare professional will evaluate a patient’s medical history and symptoms to determine if Botox treatment is appropriate.


Treatment Process and Side Effects


The Botox treatment process for migraines involves a series of injections strategically administered in specific muscle areas. The number and location of injection sites vary depending on the patient’s individual needs. Some potential side effects of Botox injections include temporary muscle weakness, localized pain or bruising at the injection site, or flu-like symptoms. However, these side effects are generally mild and transient.


Choosing a Qualified Provider


It is crucial to choose a qualified healthcare professional with expertise in administering Botox for migraines. Seek out providers who have undergone specialized training and have experience in treating migraines with Botox. A qualified provider will ensure the treatment is administered safely and effectively, maximizing the potential benefits and minimizing risks.


Integrating Botox into a Comprehensive Migraine Management Plan

Multimodal Approach to Migraine Management


Botox treatment is often just one component of a comprehensive migraine management plan. It is important to approach migraine treatment from multiple angles, including lifestyle modifications, identifying triggers, stress management techniques, and other preventive measures. A healthcare professional can help develop an individualized treatment plan that incorporates Botox along with other appropriate therapies.


Collaboration with Healthcare Providers


Collaboration with healthcare providers is essential in optimizing migraine treatment outcomes. Engage in open and honest communication with your healthcare team, sharing your symptoms, concerns, and treatment goals. This collaboration ensures a personalized approach and helps tailor the treatment plan to your individual needs.



Botox has emerged as a promising treatment option for chronic migraines, offering relief and improved quality of life for many patients. By understanding the role of Botox in migraine treatment, individuals can make informed decisions about their healthcare and explore this innovative approach to managing migraines. Consultation with a qualified healthcare professional is essential for determining candidacy, tailoring treatment plans, and achieving optimal results. With the potential benefits and scientific evidence supporting its use, Botox stands as a valuable tool in alleviating the burden of chronic migraines. Seek professional guidance to explore Botox as a potential treatment option and take a step towards a life with reduced migraine frequency and increased well-being.

Santi London, 33 Thurloe Street, London SW7 2LQ Appointments: 0207 5847000

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