Are polynucleotides: an effective aesthetic treatment

Polynucleotides, often referred to as PDRN (Polydeoxyribonucleotide), have gained some popularity in the field of aesthetic medicine in recent years. PDRN is a substance derived from DNA (usually from salmon), and it is claimed to have various benefits for the skin, including improved hydration, increased collagen production, and skin rejuvenation.

Some studies suggest that PDRN injections may help improve skin quality, reduce wrinkles, and enhance skin elasticity. These effects are believed to occur through the promotion of tissue repair and the stimulation of collagen and elastin production.

Before considering polynucleotide treatments or any other aesthetic procedures, it is crucial to consult with us to assess your individual needs, discuss the potential risks and benefits, and provide guidance on the most suitable treatment options for your specific goals. Always choose our reputable clinic to ensure your safety and the best possible outcome.

What are Polynucleotides

Polynucleotides, specifically Polydeoxyribonucleotide (PDRN), are compounds derived from DNA (deoxyribonucleic acid). DNA is a molecule found in the cells of all living organisms and contains genetic information. In the context of aesthetic treatments and regenerative medicine, PDRN is typically derived from salmon or trout sperm.

PDRN is believed to have potential benefits for the skin and tissue regeneration due to its ability to stimulate cellular repair and tissue growth. Some of the proposed benefits of PDRN in aesthetic treatments include:

Skin Rejuvenation: 

PDRN is thought to promote collagen and elastin production, which can help improve skin texture, reduce wrinkles, and enhance overall skin quality.


PDRN may have moisturizing properties that can help improve skin hydration and elasticity.

Wound Healing: 

PDRN has been used in medical settings to aid in wound healing, and it is sometimes incorporated into aesthetic treatments for its potential to enhance tissue repair.

Anti-Inflammatory Effects: 

Some studies suggest that PDRN may have anti-inflammatory properties, which could be beneficial in reducing skin redness and inflammation.

Hair Growth: 

PDRN has also been explored as a potential treatment for hair loss and thinning.

As with any cosmetic or medical procedure, it’s essential to have a consultation with a healthcare provider to discuss your specific needs, expectations, and any potential risks associated with PDRN treatments or other aesthetic procedures.

Is it similar to PRP?

Yes, PDRN (Polydeoxyribonucleotide) and PRP (Platelet-Rich Plasma) are somewhat similar in that they are both used in aesthetic and regenerative medicine to improve skin quality, stimulate tissue repair, and promote various healing processes. However, they differ in their composition and mechanisms of action:


PDRN: PDRN is derived from DNA and consists of long chains of nucleotides. It is believed to provide cellular support and promote tissue regeneration.

PRP: PRP is derived from a patient’s own blood, where it contains a concentration of platelets. Platelets contain growth factors that can stimulate tissue repair and regeneration.


Mechanism of Action:

PDRN: PDRN is thought to work by promoting cellular repair, collagen production, and tissue growth. It may have anti-inflammatory and hydrating properties.
PRP: PRP works by releasing growth factors when injected into the skin or tissues. These growth factors can stimulate cell proliferation, collagen production, and tissue healing.



PDRN: PDRN is often used in cosmetic procedures to improve skin texture, reduce wrinkles, and enhance skin quality. It may also be used for wound healing and hair growth.
PRP: PRP is commonly used in various medical and aesthetic applications, including facial rejuvenation, hair restoration, joint and tissue regeneration, and wound healing.

Both PDRN and PRP are considered minimally invasive treatments with potential benefits for skin and tissue improvement. The choice between the two may depend on the specific aesthetic concerns, the patient’s preferences, and our recommendations.