Profhilo
Skin-quality bioremodelling.
- Hydration, elasticity and firmness
- Diffuse treatment rather than contouring
- Typical two-session protocol
An injectable hyaluronic-acid treatment for skin hydration, elasticity and firmness — designed to improve skin quality without adding facial volume or changing facial shape.
A short explanation of how Profhilo works, the treatment timeline and the type of skin-quality concerns it is intended to address.
Profhilo treatment explained by the Santi team.
These treatments overlap in conversation, but they are not interchangeable. The right category depends on whether the priority is diffuse skin quality, targeted texture or facial structure.
Skin-quality bioremodelling.
Targeted skin-quality options.
Structure, contour and volume.
When the skin looks less fresh or luminous despite an appropriate skincare routine.
Fine textural change on areas such as the face, neck, décolletage or hands.
For gradual loss of skin bounce and firmness where adding volume is not the objective.
For people who want to improve the condition of the skin without altering facial shape.
Profhilo can be considered for several areas following assessment of skin quality and anatomy.
Treatment is relatively quick, although temporary bumps, redness, swelling or bruising can occur.
This Santi video looks more closely at the treatment itself — including how Profhilo is positioned within a broader skin-quality plan.
Understanding Profhilo Treatment at Santi Kensington.
We assess your medical history, skin quality, treatment area and whether Profhilo — or another approach — is the better fit.
Profhilo is placed using superficial injections. A treatment appointment is typically around 30 minutes.
The usual starting protocol is two sessions 2–4 weeks apart. Further treatment or maintenance is based on individual response and goals.
Changes are gradual. Hydration and freshness may become noticeable over the first few weeks, while texture and elasticity can continue to evolve. Individual results vary.
“Glow” is subjective. Hydration, elasticity and barrier function can be assessed more objectively. Where useful, Skin Lab provides a baseline before a skin-quality programme and a way to track change over time.
Suitable where a clinician recommends an individual session or maintenance treatment.
Two sessions, usually spaced 2–4 weeks apart.
Often discussed at around six months or later, according to response and clinical need.
Temporary injection-site bumps, redness, tenderness, swelling or bruising can occur. Your clinician will discuss expected effects, relevant risks and alternatives before treatment.
Avoid touching or massaging the treated area unless specifically advised otherwise.
Avoid intense exercise and sauna/steam exposure for around 24 hours.
Delay facials, peels and energy-based treatment in the area for around seven days unless your clinician advises differently.
Use gentle skincare and daily SPF. If you develop unusual or worsening swelling, significant pain, or concerning skin colour change, contact the clinic promptly.
Profhilo contains hyaluronic acid, but its purpose is different from conventional volumising filler. It is used to improve diffuse skin hydration, elasticity and quality rather than to create facial contour or volume.
Some people notice a change after the first treatment, but the usual starting protocol consists of two sessions, typically 2–4 weeks apart. Response varies between individuals.
The established starting protocol uses two treatments so that the second session builds on the response to the first. Your clinician can then assess whether and when maintenance is appropriate.
Hydration and freshness may become noticeable during the first few weeks. Changes in texture and elasticity can develop more gradually. Results and timelines vary.
The injections can sting briefly. Most people tolerate treatment well, and comfort measures can be discussed where needed.
Small injection-site bumps, redness, swelling or bruising may occur and commonly settle over the following day or two, although individual recovery varies.
They address different concerns. Profhilo focuses on skin quality, while anti-wrinkle treatment targets selected muscle activity. A clinician can advise whether either or both are appropriate.
There is no single “best” age. Suitability depends more on skin condition, treatment goals, medical history and examination than on age alone.
Hydration refers to water content within the skin. You can read more in our Skin Hydration guide.
Compare Profhilo with polynucleotides and other injectable skin-quality treatments.
Compare treatments →Measure hydration, elasticity, barrier function and other skin parameters.
Explore Skin Lab →For selected structural, contour or volume concerns rather than diffuse skin quality.
Explore fillers →For selected dynamic lines and muscle-related concerns following consultation.
Explore consultations →Book a consultation at Santi London in South Kensington. We can assess whether Profhilo, another skin booster, Skin Lab-guided treatment or a different approach is most appropriate.
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