The science behind PRP therapy for hair loss
PRP (platelet-rich plasma) concentrates your own growth factors to support hair follicle health. Below we outline how it works biologically, what current evidence suggests, and how we use it thoughtfully within a joined-up plan.
How PRP supports follicles (science, simplified)
Cell signalling
Platelets release growth factors that bind to follicle receptors, supporting repair pathways and helping prolong the hair growth (anagen) phase.
Micro-vascular boost
Factors such as VEGF may encourage local blood supply, helping deliver oxygen and nutrients around follicles.
Matrix support
Signals may improve dermal papilla activity and extracellular matrix support, translating into thicker, more resilient shafts.
Inside a session
- We take a small blood sample and process it in a centrifuge to concentrate platelets.
- PRP is delivered via fine injections across focus zones; numbing and technique reduce discomfort.
- Aftercare is simple: avoid heavy scalp manipulation for 24–48 hours and we review progress with photos.
What the research suggests
Encouraging trends
Many small studies and reviews report improvements in hair counts and shaft calibre in pattern thinning after a short PRP series.
Benefits usually appear gradually over months and are most consistent when PRP is part of a wider plan that supports scalp health and follicle viability.
Why results vary
- PRP preparation differs (single vs double spin, platelet concentration, leukocyte content).
- Injection depth, spacing, and cadence vary between protocols.
- Patient variables matter (stage/duration of loss, hormones, nutrition, stress, inflammation).
Larger, standardised trials will refine predictability.
Limitations, safety & sensible expectations
Not a cure-all
PRP is supportive biology, not a cure. It tends to help most in early-to-moderate thinning rather than advanced loss or scarring conditions.
Side effects
Usually mild and short-lived (redness, tenderness). We review rare risks at consultation and maintain sterile technique throughout.
Joined-up care
Scalp health, nutrition and stress can influence outcomes. We keep plans simple, sustainable and monitored over time.
What to expect at Santi
1) Clinical assessment
History, photos and scalp exam (± dermoscopy) to define pattern, triggers and realistic goals.
2) Measured plan
Where appropriate, we schedule 3 sessions 4–6 weeks apart, then review at ~8–12 weeks.
3) Maintain & review
Simple home care plus maintenance every 6–12 months with like-for-like photography.
Further reading
Deep-dives on PRP, expectations and complementary factors — written by our team.
What is PRP and how does it work?
The process, from blood draw to reinfusion.
The benefits of PRP for hair loss
What PRP may help with — and where it won’t.
PRP benefits & risks
A balanced look at safety, efficacy and limitations.
Is PRP right for you?
Candidacy, timelines and sensible expectations.
What to expect during PRP
Sensation, duration and aftercare.
How to prepare for PRP
Simple steps before your session.
PRP vs exosomes vs polynucleotides
How these approaches differ and when each may fit.
Female hair loss explained
Patterns, triggers and how we plan care.
Frequently asked questions
How many sessions are typical?
Often three sessions at 4–6-week intervals, followed by a review. Maintenance is commonly every 6–12 months, adjusted to goals and response.
Is PRP painful?
We numb the scalp first and use gentle technique. You may feel pressure or mild stinging in some areas; most clients tolerate it well.
When might PRP be less suitable?
Scarring alopecias or advanced loss may respond less predictably. Auto-immune patterns (e.g., alopecia areata) usually require dermatologist-led care — we can coordinate.
What are the risks?
Typically temporary redness or tenderness at injection sites. Rare complications are discussed at consultation; we use sterile technique and medical oversight.