Hair & Scalp Health

The science behind PRP therapy for hair loss

PRP (platelet-rich plasma) concentrates your own growth factors to support hair follicle health. Below we outline how it works biologically, what current evidence suggests, and how we use it thoughtfully within a joined-up plan.

What PRP isA small blood draw spun to concentrate platelets; reinjected into the scalp
Key growth factorsPDGF, VEGF, IGF-1, EGF — signalling for repair, microcirculation & follicle support
What studies reportTrends toward increased hair density/shaft thickness in many small trials
Typical cadence3 sessions, 4–6 weeks apart → review; maintenance every 6–12 months
Best candidatesEarly-to-moderate pattern thinning; works best as part of a wider plan

How PRP supports follicles (science, simplified)

Cell signalling

Platelets release growth factors that bind to follicle receptors, promoting cellular repair pathways and prolonging the hair growth (anagen) phase.

Micro-vascular boost

Factors like VEGF encourage local blood supply, helping deliver oxygen and nutrients around follicles.

Matrix support

Signals may improve extracellular matrix and dermal papilla activity, supporting thicker, more resilient shafts.

Inside a session

  • We take a small blood sample and process it in a centrifuge to concentrate platelets.
  • The PRP is delivered via fine injections across focus zones; numbing and gentle technique reduce discomfort.
  • Aftercare is simple; we avoid strenuous scalp manipulation for 24–48 hours and review with photos.

What the research suggests

Encouraging trends

Multiple small clinical studies and reviews report improvements in hair counts and shaft calibre for pattern thinning when PRP is used over several sessions.

Benefits tend to appear gradually (over months), and are most consistent when PRP is combined with a broader plan (e.g., scalp care, nutrition checks, sensible device use).

Why results vary

  • Different PRP preparation methods (single vs double spin; leukocyte content).
  • Injection depth, spacing and session cadence differ between studies.
  • Patient variables (age, duration of loss, hormonal/nutritional factors).

Larger, standardised trials will help refine protocols and predictability.

Limitations, safety & sensible expectations

Not a cure-all

PRP is supportive biology, not a cure. It tends to help most in early-to-moderate thinning rather than advanced loss or scarring conditions.

Side effects

Typically mild and short-lived (redness, tenderness). Rare risks are discussed at consultation; we maintain sterile technique.

Joined-up care

Scalp health, nutrition and stress management can influence outcomes. We keep plans simple, sustainable and monitored.

What to expect at Santi

1) Clinical assessment

History, photos and scalp exam (± dermoscopy) to identify pattern, triggers and realistic goals.

2) Measured plan

Where appropriate, we schedule 3 sessions 4–6 weeks apart, then review at 8–12 weeks.

3) Maintain & review

Simple home care and periodic maintenance (6–12 months) with like-for-like photography.

Pricing at Santi: Plastic surgeon consultation £220 · PRP with Biotin £500.

Further reading

Deep-dives on PRP, hormones and what to expect — written by our team.

Frequently asked questions

How many sessions are typical?

Often three sessions at 4–6-week intervals, followed by a review. Maintenance is commonly every 6–12 months, adjusted to goals and response.

Is PRP painful?

We use numbing and gentle technique. You may feel pressure or mild stinging in areas; most clients tolerate it well.

When might PRP be less suitable?

Scarring alopecias or advanced loss may respond less predictably. Auto-immune patterns (e.g., alopecia areata) usually require dermatologist-led care — we can coordinate.

What are the risks?

Typically temporary redness or tenderness at injection sites. Rare complications are discussed at consultation; we use sterile technique and medical oversight.

Curious if PRP is right for you?
Plastic surgeon consultation £220 · PRP with Biotin £500