Superficial botulinum toxin technique — evidence overview
Important: Botulinum toxin is a prescription-only medicine in the UK. This page is for general education only and does not advertise prescription treatments. Any decision about care can only be made after a face-to-face assessment with an appropriate prescriber.
What is the superficial technique?
The superficial botulinum toxin technique (sometimes called “micro-botulinum toxin” or colloquially “micro-botox”) involves very small aliquots placed into the upper dermal layer rather than deeper intramuscular sites. The approach is primarily discussed for fine textural change and skin smoothness, rather than muscle relaxation.
This page summarises published research for educational purposes only.
Proposed mechanisms
- Reduced contribution of superficial muscle fibres, softening fine dynamic lines.
- Possible sebum modulation observed in limited studies.
- Occasional improvement in mild facial flushing and sweating through reduced gland activity.
Effects are temporary and vary by individual, dose, and technique.
What does the evidence say?
Summary of findings across small-scale publications:
- Fine line and texture improvement reported in several small prospective studies.
- Temporary reduction in sebaceous output observed in pilot studies.
- Results often subtle and operator-dependent; evidence base remains limited.
Safety, limitations & suitability
Safety notes
- Common transient effects: mild redness or pinpoint bruising.
- Inappropriate depth may cause surface irregularities or asymmetry.
- Assessment by a qualified prescriber is required before any prescription-based procedure.
Unsuitable situations
Pregnancy, breastfeeding, certain neuromuscular conditions, or medication interactions may contraindicate use.
Aftercare themes (educational)
Typical aftercare includes avoiding pressure or rubbing for several hours and following clinician guidance if applicable.
References
- Journal of Cosmetic and Laser Therapy (2008): Micro-injections of botulinum toxin for sebum and pore size. DOI/PMID.
- Dermatologic Surgery (2015): Superficial botulinum toxin for perioral fine lines. DOI/PMID.
- Dermatologic Therapy (2014): Botulinum toxin for hyperhidrosis—overview. DOI/PMID.
- Journal of Cutaneous and Aesthetic Surgery (2018): Technique and contour effects with superficial micro-aliquots. DOI/PMID.
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