What Are the Best Supplements for Rosacea?

Rosacea is a chronic inflammatory skin condition influenced by barrier integrity, the microbiome, vascular sensitivity and immune response. While supplements do not “cure” rosacea, certain evidence-supported nutrients can help strengthen the skin barrier, reduce flare triggers and support overall skin resilience.

Important: Supplements should complement — not replace — prescription or professional advice. At Santi, we combine nutrition, skin-barrier repair and diagnostic testing through our Skin Lab.

1. Supplements That Support the Skin Barrier

A compromised skin barrier is one of the strongest contributors to rosacea flares. These nutrients help reinforce the barrier and reduce sensitivity.

Omega-3 Fatty Acids (EPA & DHA)

Omega-3s help reduce inflammatory signalling and improve barrier lipid composition. Best sources: high-quality fish oil, krill oil, algae-based omega-3.

Evening Primrose Oil (GLA)

GLA supports ceramide production and barrier repair — often helpful for dry, reactive rosacea types.

Vitamin D

Low vitamin D is common in inflammatory skin conditions. Supplementation may support immune balance and reduce flare frequency.

2. Supplements That Support the Gut–Skin Axis

Rosacea is closely linked with gut health, including small intestinal bacterial overgrowth (SIBO) and microbiome imbalance.

Probiotics

Look for targeted strains studied in inflammatory skin responses, including:

  • Lactobacillus rhamnosus GG
  • Lactobacillus reuteri
  • Bifidobacterium longum

Zinc

Zinc supports immune regulation, may reduce redness and assists with skin healing. Useful for pustular rosacea types.

Quercetin + Bromelain

A natural antihistamine combination that may help reduce redness and heat sensitivity.

3. Supplements That May Help Reduce Redness & Vascular Flares

These supplements may help reduce flushing, burning sensations and vascular reactivity.

Pycnogenol (French Maritime Pine Bark Extract)

Shown to improve microcirculation, reduce oxidative stress and support capillary strength.

Niacinamide (Vitamin B3)

Can be taken as a low-dose supplement or applied topically. Supports barrier repair, reduces inflammation and improves skin resilience.

Vitamin C (Low-Acid Form)

Non-acidic forms (such as sodium ascorbate) support capillary health without triggering flushing.

4. Supplements That Help Reduce Rosacea Triggers

Anti-Inflammatory Complexes

Curcumin, ginger and resveratrol blends may help with systemic inflammation related to diet and stress.

Magnesium

Helps regulate stress response — a known trigger for sudden flushing.

Green Tea Extract (Decaffeinated)

Contains calming polyphenols that may reduce redness and heat reactivity.

Want clarity on what's driving your rosacea?

Through Santi Skin Lab, we analyse hydration, barrier function, collagen integrity and inflammation patterns to tailor a personalised plan.

Explore the Skin Lab

5. How to Choose Supplements Safely

  • Choose reputable brands with third-party testing
  • Avoid high-dose vitamin B3 (niacin) — it can worsen flushing
  • Monitor interactions with prescribed rosacea treatments
  • Introduce one supplement at a time and track changes

Rosacea Supplements — FAQs

Do supplements cure rosacea?

No — rosacea is chronic and multifactorial. Supplements can support barrier repair and reduce flare triggers but do not cure it.

How long until supplements help?

4–8 weeks is typical, depending on barrier health, triggers and gut function.

Should I take probiotics for rosacea?

They can help when microbiome imbalance contributes to symptoms, but choose targeted strains and avoid unnecessary multi-blends.

Which supplements reduce flushing?

Pycnogenol, quercetin, omega-3 and magnesium are most frequently used to reduce heat sensitivity and redness.